PXIE-6366
May 27, 2026

PXIE-6366

The PXIe-6366 is a 3U X-series multi-functional synchronous sampling data acquisition module launched by National Instruments (NI). Its part number is 781057-01NI. It integrates 8 synchronous analog inputs, 2 analog outputs, 24 digital I/Os, and 4 32-bit counters. It is specifically designed for high-speed, multi-channel synchronous acquisition and control, featuring high throughput, high precision, and strong real-time performance. It is widely used in scenarios such as mid-frequency digitization, transient recording, vibration acoustics, industrial control, and scientific research testing.

Description

Model Explanation

PXIe: PXI Express bus, Gen2 x4 link, bandwidth 1.6 GB/s.

6366: X series DAQ module, 8 channels of synchronous AI + 2 channels of AO + 24 channels of DIO configuration from NI.

Core Identifier: 2 MS/s synchronous sampling per channel, 16-bit resolution, NI-STC3 timing engine from NI. Technical Specifications

Analog Input (AI)

Channels: 8 differential, synchronous sampling NI.

Resolution: 16 bits, no bit loss NI.

Sampling Rate: 2 MS/s per channel, total throughput 16 MS/s NI.

Range: ±1 V, ±2 V, ±5 V, ±10 V.

Input Protection: Maximum ±11 V, DC coupling NI.

Absolute Precision: 2688 μV (typical value).

Analog Output (AO)

Channels: 2 NI.

Resolution: 16 bits NI.

Update Rate: 3.33 MS/s NI.

Output Range: ±10 V, drive capability ±5 mANI.

Output Resistance: 0.2 Ω (typical value).

Digital I/O (DIO)

Channels: 24, 3.3 V TTL/CMOS level NI.

Hardware Timing: 8 channels up to 10 MHz, supports PWM, mode I/O, trigger NI.

Counter / Timer

4 32-bit counters NI.

Function: PWM generation, encoder measurement, frequency / event counting NI.

General Electrical and Environmental

Power Consumption: Approximately 20 W (+3.3 V 4.75 W, +12 V 15.6 W).

Operating Temperature: 0 °C to 55 °C NI.

Calibration: Factory calibration, recommended calibration once every 2 years NI.

Size: 1 slot 3U PXIe, weight approximately 0.45 kg.

Interface and Communication Configuration

Host Interface: PXIe Gen2 x4, 1.6 GB/s high-speed data transfer, supports DMA stream reading and writing NI.

Front Panel Connector: 68-pin VHDCI female connector, used for analog/digital signal wiring.

Timing and Synchronization: Onboard NI-STC3 timing engine, 10 ns resolution, 50 ppm accuracy; supports PXI trigger bus, star trigger, external 10 MHz reference clock, achieve precise multi-module synchronization NI.

Trigger Function: Analog/digital edge trigger, window trigger, supports re-triggerable tasks NI.

Driver Software: Standard NI-DAQmx driver, compatible with Windows and real-time systems, provides API for simplified configuration, synchronization and measurement process NI. Core function

8-channel synchronous high-speed acquisition: Each channel samples at 2 MS/s synchronously, ensuring consistent phase of multi-channel signals, suitable for synchronous measurement of vibration, acoustic, and intermediate-frequency signals by NI.

High-precision mixed signal control: 16-bit AI/AO provides precise measurement and waveform generation, and an independent timing engine supports asynchronous complex tasks for AI/AO/DIO by NI.

Flexible triggering and synchronization: Rich triggering sources and multi-module synchronization capabilities meet the needs of transient signal capture and multi-device collaborative testing by NI.

High-throughput data streaming transmission: The PXIe bus and DMA ensure continuous data is transmitted at high speed, suitable for long-term high-speed recording by NI.

Multifunctional integration: Integrated analog I/O, digital I/O, and counter reduce system slot occupation and hardware cost by NI. Applicable scenarios

Intermediate Frequency (IF) Digitalization and Transient Signal Recording: High-speed synchronous acquisition of radar and communication IF signals by NI.

Telecommunication Equipment Manufacturing Testing: Function and performance testing of ISDN, ADSL, and POTS interfaces by NI.

Ultrasonic/Sonar and High-Energy Physics Experiments: Multi-channel synchronous signal acquisition and analysis by NI.

Vibration and Noise Monitoring: Multi-point synchronous vibration testing of motors, engines, and structural components by NI.

Hardware-in-the-Loop (HIL) Real-time Simulation: Real-time I/O and closed-loop testing of automotive and aerospace control systems by NI.

Industrial Automation and Process Control: High-speed closed-loop control, multi-parameter synchronous monitoring by NI.

User Manual

Key Usage Points

Installation: Insert into an empty slot of the 3U PXIe chassis, lock the fixing screws, no external power supply required by NI.

Preheating: Power on and preheat for 15 minutes to ensure measurement accuracy by NI.

Cabling: Use shielded twisted-pair cables for analog signals, separate the digital signals from the analog signal ground lines to avoid interference by NI.

Range Selection: Select the appropriate range based on the amplitude of the input signal to avoid module damage due to over-range by NI.

Driver Installation: Install the NI-DAQmx driver to complete hardware identification and configuration by NI.

Maintenance and Calibration

Cleaning: Regularly wipe the front panel and connectors with a dry soft cloth to avoid dust accumulation affecting contact reliability by NI.

Calibration Cycle: Conduct calibration once every 2 years, you can choose to calibrate with NI's official or a qualified third-party calibration institution by NI.

Storage: When not in use for a long time, store in a dry, cool environment to avoid high temperature, humidity, and static damage by NI.

Troubleshooting: When encountering abnormalities, check the wiring, power supply, and driver configuration, and contact NI technical support if necessary by NI.


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