I. Basic Information

Model: PCIe-6321 (X Series MIO)

Part Number: 781044-01

Bus: PCIe ×1 (Gen2, bus-powered)

Status: In Stock (Active)

Driver: NI-DAQmx (recommended), compatible with traditional NI-DAQ

System: Windows 7/10/11 (32/64-bit), Linux

II. Core Specifications (Easy to Understand)

✅ Analog Input AI (16 channels)

Channels: 16 single-ended (SE) / 8 differential (DIFF) NI

Resolution: 16 bits (no bit loss) NI

Maximum Sampling Rate: 250kS/s (single / multi-channel) NI

Voltage Range (software selectable): ±10V, ±5V, ±2V, ±1V

Input Impedance: 10GΩ; Overvoltage Protection: ±25V NI

FIFO: 4095 samples NI

?? Analog Output AO (2 channels)

Channels: 2 voltage outputs NI

Resolution: 16 bits

Maximum Update Rate: 900kS/s (single / dual channels) NI

Range: ±10V, ±5V

Drive: ±5mA / channel

??️ Digital I/O DIO (24 channels)

Channels: 24 bidirectional TTL (5V), including 16 PFI (programmable function interface)

Modes: Input / Output can be configured by software; supports static I/O, high-speed waveform, change detection trigger

Rate: Up to 10MHz (hardware timing)

⏱️ Counter / Timer (4 channels)

32-bit counter, 100MHz base (STC3)

Functions: Quadrature encoder, PWM, event counting, frequency measurement, pulse generation

Each channel FIFO: 127 samples

III. Interfaces and Physical

Connector: 68-pin VHDCI (high density) NI

Size: Full-height PCIe card (16.8×11.1cm)

Power Supply: PCIe bus power supply (≈10W) NI

Temperature: 0°C ~ 55°C (operating)

IV. Typical Applications

Teaching / Laboratory Automation: Basic data acquisition, closed-loop control experiments

Sensor Measurement: Temperature, pressure, strain, voltage signals

Small Test System: Component verification, prototype testing, low-speed automation

Lightweight Motion Control: Encoder feedback, PWM output, event counting

V. Series Upgrade / Replacement (As Needed)

✅ Direct Upgrade (Higher Sampling Rate)

PCIe‑6341: 16AI/2AO/24DIO, 500kS/s, PCIe ×1, in stock NI

PCIe‑6361: 16AI/2AO/24DIO, 2MS/s, PCIe ×1, in stock NI

✅ Channel Expansion (More AI/AO/DIO)

PCIe‑6353: 32AI/4AO/48DIO, 1.25MS/s, PCIe ×1, in stock NI

PCIe‑6363: 32AI/4AO/48DIO, 2MS/s, PCIe ×1, in stock NI

✅ Low-cost Replacement (M Series)

PCIe‑6221: 16AI/2AO/24DIO, 250kS/s, PCIe ×1, in stock VI. Common Questions

✅ Compatible with 6221: Pin / Cable compatibility (68-pin VHDCI), simple software migration

✅ 4-channel counter: More than the old M series (2 channels), suitable for multi-encoder / PWM scenarios

⚠️ Sampling rate 250kS/s: Not suitable for high-speed signals (e.g. > 100kHz), prefer 6361 instead